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11:00-13:00 Liver Forum
"Blue" Hall | Moderator: Dr. Yoav Lurie
Sponsored by:
11:00-11:30 In the Footsteps of the Liver
Dr. Tamar Berger, Beilinson Hospital
11:30-12:00 DECOPPERING מחלת וילסון: נחושים ל-
Dr. Ella Wiezmann, Rambam Medical Center
12:00-12:30 Tacrolimous Vs Cyclosporine after liver transplantation
Dr. Oranit Cohen- Ezra, Tel Hashomer
12:30-13:00 Treating Hepatitis C beyond AASLD/ EASL Recommendations
Dr. Yaakov Maor, Kaplan Medical Center
13:00-13:30 Light Lunch
Rrgistration Desk area- Lobby Floor
13:30-13:45 Opening
"Blue" Hall
13:30-13:35 Greetings-Prof. Eli Zuckerman, IsASL Chairman
13:35-13:45 Hepatology 2017- לאן?
Prof. Ran Tur- Kaspa Director, Liver Institute, Beilinson Hospital
13:45-15:55 Session 1
"Blue" Hall
Chairs: Prof. Rafi Bruck, Dr. Rawi Hazan
13:45-10:53 Novel anti-LOXL2 inhibitor paves the way for macrophage-mediated collagen degradation in experimental liver fibrosis
Mordehay Kelpfish 2 , Milena Vugman 1 , Eli Brazowski 1 , Chen Varol 1 , Irit Sagi 2
1 The Research Center for Digestive Tract and Liver Diseases and Department of Clinical Microbiology and Immunology, Tel-Aviv Sourasky Medical Center and Tel-Aviv University, Israel
2 Department of Biological Regulation, Weizmann Institute of Science, Israel
13:53-14:01 The PARP-1 inhibitor 3-aminobenzamide prevents Concanavalin A-induced acute hepatitis in mice by a joint anti-inflammatory and anti-oxidative mechanism
Joram Wardi 1 , Orna Ernst 4 , Anna Lilja 4 , Hussein Aeed 1 , Sebastian Katz 4 , Dolev Katz 4 , Olga Bernadsky 2 , Rajendar Kandhikonda 5 , Yona Avni 1 , Roy Weinstain 5 , Alexander Biro 3 , Tsaffrir Zor 4
1 Gastroenterology, Wolfson Medical Center, Israel
2 Pathology, Wolfson Medical Center, Israel
3 Nephrology, Wolfson Medical Center, Israel
4 Biochemistry and Life Sciences, Life Sciences, Tel-Aviv University, Israel
5 Molecular biology & ecology of plants, Tel-Aviv University, Life Sciences, Israel
14:01-14:09 Thiopurine metabolites measurement in adult patients with autoimmune hepatitis
Hisham Sholy , Ella Veitsman , Tarek Saadi
Liver unit, Rambam Health Care Campus, Israel
14:09-14:17 Namodenoson (CF102) Prevents Progression of Liver Fibrosis
Johnny Amer 1 , Rifaat Safadi 1 , Ahmad Salhab 1 , Shira Cohen 2 , Pnina Fishman 2
1 Liver & Gastroenterology Units, Hadassah-Hebrew University Hospital., Israel
2 Can-Fite BioPharma Ltd., Can-Fite BioPharma Ltd., Israel
14:17-14:25 Metabolic and cardiovascular co-morbidities are associated with severe complications following Transjugular Intrahepatic Portosystemic Shunt :a 10 year single center experience
Neta Gotlieb 1 , Jonathan Brill 2 , Shiri Sherf Dagan 1 , Isaac Kori 3 , Oren Shibolet 1
1 department of gastroenterology and liver diseases, Tel-aviv medical center and the Sackler faculty of medicine, Tel-Aviv, Israel, Israel
2 Sackler faculty of medicine, Tel-Aviv university, Tel-Aviv, Israel, Israel
3 Interventional radiology, Tel-Aviv medical center and the Sackler faculty of medicine, Tel-Aviv, Israel, Israel
14:25-14:33 Effect of the autonomic nervous system on splanchnic circulation before andafter meals
Farid Zreik , Reshef Meshulam , Oren Shibolet , Jacob Giris
Medicine F, J. Recanati Autonomic Dysfunction Center, Tel Aviv Sourasky Medical Center & Faculty of Medicine, Israel
14:33-14:41 Amiodarone induced adipose tissue endoplasmic reticulum stress and lipolysis may contribute to hepatic lipid accumulation
Einav Hubel-Manor , Inbal Houri , Roy Avraham , Isabel Zvibel , Oren Shibolet
Gastroenterology Institute, Sackler Faculty of Medicine, Tel-Aviv University, Israel
14:45-15:25 PBC-Panoramic View of New and emerging treatments
Prof. Gideon Hirschfield
Professor of Autoimmune Liver Disease at the University of Birmingham, and Honorary Consultant Transplant
Hepatologist at Queen Elizabeth Hospital, University Hospitals Birmingham, UK
Sponsored by
15:25-15:50 Coffee Break, Visit to the Poster Exhibit & Exhibit Hall
15:50-18:00 Session 2
"Blue" Hall
Chairs: Dr. Amir Shlomai, Dr. Tarek Saadi
15:50-16:00 The Dual CCR2/CCR5 Inhibitor Cenicriviroc Ameliorates Murine Primary Biliary Cholangitis
Debby Reuveni 1 , Debby Reuveni 1 , Ayelet Kaminitz 1 , Siwar Assi 1 , Patrick Leung 3 , Pamela Vig 4 , Eli Brazowski 2 , Oren Shibolet 1 , Eric Gershwin 3 , Ehud Zigmond 1
1 The Research Center for Digestive Diseases, Gastroenterology and Liver disease institute, Tel Aviv-Sourasky Medical Center, Israel
2 Department of Pathology, Sourasky Medical Center, Israel
3 Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, USA
4 Allergen, Allergen plc, USA \
16:00-16:20 Hot Topic 1-PSC –Clinical challenges in practice
Prof. Gideon Hirschfield
Professor of Autoimmune Liver Disease at the University of Birmingham, and Honorary Consultant Transplant
Hepatologist at Queen Elizabeth Hospital, University Hospitals Birmingham, UK
16:20-16:28 Point Shear Wave Elastography Method for Assessing Liver Stiffness in Different Etiologies of Liver Diseases – A Prospective study
Tarek Saadi 1 , Johad Khoury 1 , Widad Toukan 1 , Hisham Sholy 1 , Rimma Krimasky 1 , Vered Ben Hakoon 1 , Ella Veitzman 1 , Yaakov Baruch 1 , Diana Gaitini 2
1 Liver Unit, Rambam: Human Health Care Campus, Haifa 31096, Israel, Haifa, Israel, Israel
2 Radiology department, Rambam: Human Health Care Campus, Haifa 31096, Israel, Haifa, Israel, Israel
16:30 -17:15 HCV: lesson learned from clinical studies to real world data
Prof. Steven Flamm
Division of Hepatology ,Northwestern University Feinberg School of Medicine ,Chicago, Illinois, USA
Sponsored by
17:15-17:23 Vitamin D antagonizes the expression of genes that are epigenetically regulated by Hepatitis C virus
Romy Zemel 1 , Noa Rapaport 1 , Shira Perez 2,3 , Eteedal Morad 3 , Marcela Karpuj 4 , Amiram Ravid 5 , Meital Gal-Tanamy 2 , Izhak Haviv 3 , Ran Tur-Kaspa 6,7
1 Molecular Hepatology Lab., Tel-Aviv University , FMRC, Israel
2 Molecular Virology Lab., Bar-Ilan University, Faculty of Medicine in the Galilee, Israel
3 Cancer Personalized Medicine and Diagnostic Genomics Lab, Bar-Ilan University, Faculty of Medicine in the Galilee, Israel
4 Genomic Center, Bar-Ilan University, Faculty of Medicine in the Galilee, Israel
5 Molecular Endocrinology, Tel-Aviv University, FMRC, Israel
6 Liver Institute, Rabin Medical Center, Beilinson Hospital, Israel
7 Faculty of Medicine in the Galilee, Bar-Ilan University, Israel
17:25-17:55 Novel treatment options for Hepatitis B and D Virus infection: Entry Inhibition as a potent concept to prevent intraheptic spread of HBV cccDNA and HDV RNA
Prof. Stephan Urban
Head, Translational Virology unit , Department of Infectious Diseases, Molecular Virology Heidelberg University Hospital, Germany
17:55-18:10 Coffee Break, Visit at the Poster Exhibit & Exhibit Hall
18:10-19:30 Session 3
"Blue" Hall
Chairs: Dr. Tania Berdichevski, Dr. Marius Braun
18:10-18:18 Increased killer B cells: Are they associated with increased viral load and autoimmunity in patients with chronic HCV infection?
Eli Zuckerman 1 , Nasren Eiza 2 , Mattias Karlebach 3 , Tova Rainess 3 , Yair Goldberg 2 , Elias Toubi 2 , Zahava Vadasz 2
1 Liver Unit, Carmel Medical Center, Technion Faculty of Medicine, Israel
2 Division of Allergy & Clinical Immunology, Bnai Zion Medical Center, Israel
3 Institute of Gastroenterology, Bnai Zion Medical Center, Israel
18:20-19:05 It's all about the Pan- moving forward with HCV treatment
Dr. Ashley Brown
Consultant Hepatologist, Imperial College Healthcare NHS Trust
St. Mary’s Hospital, UK
Sponsored by
19:05-19:13 Prospective assessment of the impact of successful DAAs treatment on liver fibrosis stage and predictors of fibrosis regression in patients with chronic hepatitis C
Yana Davidov-Derevyanko 1 , Yeruham Kleinbaum 1,3 , Yael Inbar 1,3 , Oranit Cohen-Ezra 1,4 , Ella Veitsman 2 , Tanya Berdichevsky 1 , Perez Weiss 1 , Maria Lihter 1 , Sima Katerginsky 1,3 , Avishag Hassid 1 , Keren Tzaraf 1 , Ziv Ben-Ari 1,4
1 Liver Disease Center, Sheba Medical Center, Israel
2 Liver Disease Center, Rambam Medical Center, Israel
3 Department of Radiology, Sheba Medical Center, Israel
4 Sackler School of Medicine, Tel Aviv University, Israel
21:15-23:00 Concert- Daniel Solomon & Dana Adini
21:15-Opening Doors
21:30- Concert Strats
"Tarshish" Hall